COMPUTED DESCRIPTORS
| Molecular Weight | 3903.3 g/mol |
|---|---|
| XLogP3 | -18.7 |
| Hydrogen Bond Donor Count | 61 |
| Hydrogen Bond Acceptor Count | 61 |
| Rotatable Bond Count | 115 |
| Exact Mass | 3901.8669088 g/mol |
| Monoisotopic Mass | 3900.8635539 g/mol |
| Topological Polar Surface Area | 1810 Ų |
| Heavy Atom Count | 273 |
| Formal Charge | 0 |
| Complexity | 9390 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 41 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
A pancreatic beta-cell hormone that is co-secreted with INSULIN. It displays an anorectic effect on nutrient metabolism by inhibiting gastric acid secretion, gastric emptying and postprandial GLUCAGON secretion. Islet amyloid polypeptide can fold into AMYLOID FIBRILS that have been found as a major constituent of pancreatic AMYLOID DEPOSITS.