RMC-4998
| Price | USD54476.00 |
| Packge | 1000kg |
- Min. Order:100kg
- Supply Ability:1000
- Time:2025-10-11
Product Details
- Product NameRMC-4998
- CAS No.2642037-07-6
- MFC57H74N8O7
- MW983.25
- AppearanceSolidWhite to off-white
- density 1.24±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
RMC-4998 is a tri-complex inhibitor and KRASG12C inhibitor. RMC-4998 targets the active or GTP-bound state of KRASG12C. Disruption of effector binding by RMC-4998 inhibited downstream ERK signaling in KRASG12C mutant cancer cell models with an IC50 ranging between 1 and 10 nM. RMC-4998 had median IC50 of 0.28 nM and selectivity index of 1450. Of note, both the potency and the selectivity index of RMC-4998 and RMC-6291 were greater than those of adagrasib.
Chemical Structure
RMC-4998
CAS#2642037-07-6
Theoretical Analysis
Name: RMC-4998
CAS#: 2642037-07-6
Chemical Formula: C57H74N8O7
Exact Mass: 982.5680
Molecular Weight: 983.27
Elemental Analysis: C, 69.63; H, 7.59; N, 11.40; O, 11.39
Company Profile Introduction
Fejan Mansuri Limited India
India
- Since:1991-07-16
- Address: 16/259 ‘’Krishna’’ 1st Floor, behind Shiv Mandir Road, Vidya Nagar, Chhattisgarh 495004
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