Otamixaban
| Price | USD1.00 |
| Packge | 1g |
- Min. Order:1g
- Supply Ability:1ton
- Time:2020-01-13
Product Details
- Product NameOtamixaban
- CAS No.193153-04-7
- EINECS No.200-258-5
- MFC25H26N4O4
- MW446.5
- AppearancePowderLight yellow to yellow
- density 1.25
- storage temp. Store at -20°C
▼
▲
Common Name
Density
1.3±0.1 g/cm3
Boiling Point
N/A
Molecular Formula
C25H26N4O4
Melting Point
N/A
MSDS
N/A
Flash Point
N/A
▼
▲
Use of Otamixaban
Otamixaban(FXV673) is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa.IC50 value:Target: Factor Xa Otamixaban is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. In vivo experiments have demonstrated that Otamixaban is highly efficacious in rodent, canine and porcine models of thrombosis. In addition, recent clinical findings indicate that Otamixaban is efficacious, safe and well tolerated in humans and therefore has considerable potential for the treatment of acute coronary syndrome. This review article chronicles the discovery and pre-clinical data surrounding the fXa inhibitor Otamixaban as well as the recent clinical findings in humans.
▼
▲
Name
methyl (2R,3R)-2-[(3-carbamimidoylphenyl)methyl]-3-[[4-(1-oxidopyridin-1-ium-4-yl)benzoyl]amino]butanoate
Synonym
▼
▲
Description
Otamixaban(FXV673) is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa.IC50 value:Target: Factor Xa Otamixaban is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. In vivo experiments have demonstrated that Otamixaban is highly efficacious in rodent, canine and porcine models of thrombosis. In addition, recent clinical findings indicate that Otamixaban is efficacious, safe and well tolerated in humans and therefore has considerable potential for the treatment of acute coronary syndrome. This review article chronicles the discovery and pre-clinical data surrounding the fXa inhibitor Otamixaban as well as the recent clinical findings in humans.
Related Catalog
References
▼
▲
Density
1.3±0.1 g/cm3
Molecular Formula
C25H26N4O4
Molecular Weight
446.498
Exact Mass
446.195404
PSA
130.73000
LogP
0.58
Index of Refraction
1.619
▼
▲
1ksn
Otamixaban
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
- Since:2014-12-17
- Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
INQUIRY