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Dicloxacillin sodium
Dicloxacillin sodium

Dicloxacillin sodium

Price USD1.00
Packge 1KG
  • Min. Order:1KG
  • Supply Ability:10000KGS
  • Time:2020-01-03

Product Details

  • Product NameDicloxacillin sodium
  • CAS No.13412-64-1
  • EINECS No.603-794-2
  • MFC19H20Cl2N3NaO6S
  • MW512.33
  • Appearancepowderwhite to off-white
  • storage temp. 2-8°C
  • Melting point 222-225°C
  • Water Solubility Soluble in water
Email:hanne@coreychem.com
wechat/whastapp:+8615670622393
hanne 858
Product Name:
Synonyms:
3-(2,6-DICHLOROPHENYL)-5-METHYL-4-ISOXAZOLYL PENICILLIN;DICLOXACILLIN SODIUM SALT HYDRATE VETRAN;DICLOXACILLIN SODIUM EPD(CRM STANDARD);DICLOXACILLIN SODIUM USP(CRM STANDARD);DICLOXACILLIN SODIUM WHO(CRM STANDARD);4-Thia-1-azabicyclo3.2.0heptane-2-carboxylic acid, 6-3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolylcarbonylamino-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate, (2S,5R,6R)-;Dicloxacillin sodium;Sodium 7-[3-(2,6-dichlorophenyl)-5-methyl-oxazol-4-yl]carbonylamino-3,3-dimet hyl-6-oxo-2-thia-5-azabicyclo[3.2.0]heptane-4-carboxylate
CAS:
MF:
C19H16Cl2N3NaO5S·H2O
MW:
510.32
EINECS:
603-794-2
Mol File:
Dicloxacillin sodium Structure
 
Dicloxacillin sodium Chemical Properties
Melting point 
222-225°C
alpha 
D20 +127.2° (water)
storage temp. 
2-8°C
solubility 
H2O: soluble50mg/mL
form 
powder
color 
white to off-white
Water Solubility 
Soluble in water
BRN 
4778711
CAS DataBase Reference
 
Safety Information
Hazard Codes 
Risk Statements 
Safety Statements 
WGK Germany 
2
RTECS 
XH8925000
HS Code 
29411099
Toxicity
LD50 in mice (g/kg): 0.9 i.v.; in rats (g/kg): 0.63 i.p.; >5 orally (Gloxhuber)
MSDS Information
 
 
Dicloxacillin sodium Usage And Synthesis
Chemical Properties
White to off-white crystalline powder
Uses
A semi-synthetic antibiotic related to Penicillin. Antibacterial.
Uses
Antibacterial;Bacterial transpeptidase inhibitor
Brand name
Dynapen (Apothecon).
General Description
The substitution of chlorine atoms on both carbons orthoto the position of attachment of the phenyl ring to the isoxazolering is presumed to enhance further the stability ofthe oxacillin congener dicloxacillin sodium, [3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]penicillin sodiummonohydrate (Dynapen, Pathocil, Veracillin) and toproduce high plasma concentrations of it. Its medicinalproperties and use are similar to those of cloxacillinsodium. Progressive halogen substitution, however, alsoincreases the fraction bound to protein in the plasma, potentiallyreducing the concentration of free antibiotic inplasma and tissues. Its medicinal properties and use are thesame as those of cloxacillin sodium.
Veterinary Drugs and Treatments
The veterinary use of dicloxacillin has been primarily in the PO treatment of bone, skin, and other soft tissue infections in small animals when penicillinase-producing Staphylococcus species have been isolated. Because of its low oral bioavailability and short halflife, other drugs with good staph coverage are usually employed.

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;
  • Since:2014-12-17
  • Address: Room 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H
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