LY-364947
| Price | USD1.00 |
| Packge | 1KG |
- Min. Order:1KG
- Supply Ability:20kg
- Time:2019-09-06
Product Details
- Product NameLY-364947
- CAS No.396129-53-6
- MFC17H12N4
- MW272.3
- Appearancepowderwhite to beige
- storage temp. 2-8°C
- Melting point >230℃ (dec.)
- Boiling point 490.8±45.0 °C(Predicted)
- density 1.283±0.06 g/cm3(Predicted)
Abby020
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LY-364947 Basic information
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Product Name:
Synonyms:
LY-364947;[3-(Pyridin-2-yl)-4-(4-quinonyl)]-1H-pyrazole;4-[3-(2-Pyridinyl)-1H-pyrazol-4-yl]-quinoline;LY364947(HTS 466284);E 616451;HTS 466284;2-[4-(Quinolin-4-yl)-1H-pyrazol-3-yl]pyridine, 3-(Pyridin-2-yl)-4-(quinolin-4-yl)-1H-pyrazole;Quinoline, 4-[3-(2-pyridinyl)-1H-pyrazol-4-yl]-
CAS:
MF:
C17H12N4
MW:
272.31
EINECS:
Product Categories:
Mol File:
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LY-364947 Chemical Properties
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Melting point
>230℃ (dec.)
storage temp.
Store at RT
solubility
DMSO: soluble2mg/mL, clear
form
powder
color
white to beige
InChIKey
IBCXZJCWDGCXQT-UHFFFAOYSA-N
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Safety Information
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Hazard Codes
Risk Statements
Safety Statements
RIDADR
UN 2811 6.1/PG 3
WGK Germany
3
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LY-364947 Usage And Synthesis
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Biological Activity
Selective inhibitor of TGF- β type-I receptor (TGF- β RI, TGFR-I, T β R-I, ALK-5) (IC 50 values are 59, 400 and 1400 nM for TGR- β RI, TGF- β RII and MLK-7K respectively). Inhibits TGF- β -dependent luciferase production in mink lung cells (p3TP lux) and growth in mouse fibroblasts (NIH 3T3) (IC 50 values are 47 and 89 nM respectively). Suppresses invasion of MDA-MB-231 breast cancer cells in a matrigel invasion assay.
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LY-364947 Preparation Products And Raw materials
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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