Metadoxine
| Price | USD3.00 |
| Packge | 3KG |
- Min. Order:1KG
- Supply Ability:100kg
- Time:2019-08-08
Product Details
- Product NameMetadoxine
- CAS No.74536-44-0
- EINECS No.277-913-8
- MFC13H18N2O6
- MW298.3
- AppearanceSolidWhite to Light Yellow
- Melting point 102-104°C
- storage temp. Sealed in dry,2-8°C
Metadoxine
Modify Date: 2019-06-16 16:59:39
▼
▲
N/A
491.9ºC at 760 mmHg
C13H18N2O6
102-104ºC
N/A
251.3ºC
▼
▲
Use of Metadoxine
Metadoxine blocks adipocyte differentiation in association with inhibition of the protein kinase A-cAMP response element binding protein (PKA-CREB) pathway.
Related searches:
4,5-bis(hydroxymethyl)-2-methyl-3-pyridinol hydrochloride (1:1) | dl-proline, 5-oxo-, compd. with n2-coco acyl-l-arginine et ester | (5-hydroxy-6-methyl-3,4-pyridinediyl)bis(methylene) dihexadecanoate | 5-oxo-l-proline - 4,5-bis(hydroxymethyl)-2-methyl-3-pyridinol (1: 1) | 4,5-bis(hydroxymethyl)-2-(2h3)methyl-3-pyridinol hydrochloride (1:1)
Names
▼
▲
Metadoxine Biological Activity
▼
▲
Metadoxine blocks adipocyte differentiation in association with inhibition of the protein kinase A-cAMP response element binding protein (PKA-CREB) pathway.
Simultaneous Metadoxine treatment notably inhibits adipogenic differentiation in a dose-dependent manner. Metadoxine treatment from day 4 through day 8 is required for inhibition of MDI-induced preadipocyte differentiation[1]. Metadoxine prevents glutathione depletion and the increase in lipid peroxidation damage caused by ethanol and acetaldehyde in HepG2 cells. In hepatic stellate cells, Metadoxine prevents the increase in collagen and attenuated TNF-α secretion caused by acetaldehyde. Thus, Metadoxine could be useful in preventing the damage produced in early stages of alcoholic liver disease as it prevents the redox imbalance of the hepatocytes and prevents TNF-α induction, one of the earliest events in hepatic damage[2].
Chemical & Physical Properties
▼
▲
491.9ºC at 760 mmHg
102-104ºC
C13H18N2O6
298.292
251.3ºC
298.116486
139.98000
Refrigerator
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
INQUIRY