Cloxacillin-13C4 SodiuM Salt

Product Name:

Synonyms:

austrastaph;prostaphlina;sodiumorbenin;sodiumsyntarpen;staphybiotic;syntarpensodiumsalt;tegopen;CLOXACILLIN SODIUM SALT HYDRATE

CAS:

MF:

C19H17ClN3O5S.Na

MW:

457.87

EINECS:

211-390-9

Product Categories:

-;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;API;A - KAntibiotics;Antibacterial;Antibiotics A to;Antibiotics A-FAntibiotics;Chemical Structure Class;Interferes with Cell Wall SynthesisAntibiotics;Mechanism of Action;Penicillins and Cephalosporins (beta-Lactams);Spectrum of Activity;Amines;Aromatics;Chiral Reagents;Heterocycles

Mol File:

 

Cloxacillin-13C4 SodiuM Salt Chemical Properties

Melting point 

170°C

storage temp. 

2-8°C

solubility 

H₂O: 50 mg/mL, clear, colorless

Water Solubility 

Soluble in water

Stability:

Stable. Incompatible with strong oxidizing agents. Refrigerate.

CAS DataBase Reference

 

Safety Information

Hazard Codes 

Risk Statements 

Safety Statements 

WGK Germany 

2

RTECS 

XH8920000

Chemical Properties

White Crystalline Powder

Uses

Cloxacillin-13C4 SodiuM Salt is an antibiotic that belongs to the group of the isoxazolylpenicillins. Cloxacillin is used to treat infections caused by species of staphylococci that produce beta-lactamase due to its inhibitory effects on beta-lactamase binding.

Uses

Cloxacillin-13C4 SodiuM Salt, an antibiotic that belongs to the group of the isoxazolylpenicillins. Cloxacillin is used to treat infections caused by species of staphylococci that produce beta-lac tamase due to its inhibitory effects on beta-lactamase binding.

Uses

Labelled S-Form of Dropropizine. Cough suppressive phenylpiperazine derivative. Antitussive.

Uses

Ropivacaine (R675000) metabolite.

Brand name

Cloxapen (GlaxoSmithKline); Tegopen (Apothecon).

Purification Methods

Purify cloxacillin sodium salt by dissolving it in isoPrOH containing 20% of H2O, and diluting with isoPrOH to a water content of 5% and chilling. Recrystallise it again in this manner. The sodium salt is collected and dried at 40o in air to give the colourless monohydrate. It is soluble in H2O (5%), MeOH, EtOH, pyridine and ethylene glycol. [Doyle et al. J Chem Soc 5838 1963, Naylor et al. Nature 195 1264 1962.] (
) -Cocaine {ecogonine methyl ester benzoate, 2 -carbomethoxy-3--benzoxytropane, methyl 1R -(exo,exo)]-3-(benzoyloxy)-2-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate}