Vinflunine
| Price | USD1.00 |
| Packge | 1KG |
- Min. Order:1KG
- Supply Ability:2000kg
- Time:2019-08-06
Product Details
- Product NameVinflunine
- CAS No.162652-95-1
- EINECS No.1806241-263-5
- MFC45H54F2N4O8
- MW816.94
- density 1.39±0.1 g/cm3(Predicted)
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Product Name:
Synonyms:
VINFLUNINE;Vinflunine 162652-95-1;20',20'-Difluoro-3',4'-dihydrovinorelbine;4'-Deoxy-20',20'-difluoro-5'-norvincaleukoblastine;4'-Deoxy-20',20'-difluoro-8'-norvincaleukoblastine;Vinflunine Tartrate
CAS:
MF:
C45H54F2N4O8
MW:
816.93
EINECS:
1806241-263-5
Product Categories:
Mol File:
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Vinflunine Chemical Properties
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CAS DataBase Reference
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Safety Information
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Vinflunine Usage And Synthesis
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Description
Vinflunine (also referred to as PM391) is a semisynthetic analog of the natural vinca alkaloids vinblastine and vincristine that was approved by the European Medicines Agency (EMEA) in 2009 for the treatment of adult patients with advanced or metastatic transitional cell carcinoma of the urothelial tract after failure of a prior platinum-containing regimen. Vinflunine is synthesized from anhydrovinblastine in a superacid media (HF-SbF5) and in the presence of a chlorinated solvent like CHCl3 or CCl4.
Originator
Pierre Fabre (France)
Definition
ChEBI: An organic heteropentacyclic compound and an organic heterotetracyclic compound that is vinorelbine in which the tetrahydropyridine moiety of the heterotetracyclic part of the molecule has been redced to the corresponding piperidine, and in which the ethy group attached to this ring has been replaced by a 1,1-difluoroethyl group.
Brand name
Javlor
Company Profile Introduction
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
- Since:2014-12-17
- Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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