530-62-1 N,N-Carbonyldiimidazole (CDI) 99%

Chemical Name: 1,1'-Carbonyldiimidazole (CDI)
CAS No.: 530-62-1
Molecular Formula: C₇H₆N₄O
Molecular Weight: 162.15 g/mol
Synonyms: N,N'-Carbonyldiimidazole, Carbonyl Diimidazole, CDI, Di(1H-imidazol-1-yl)methanone, 1,1'-Carbonylbis(1H-imidazole)

Physical & Chemical Properties

• Appearance: White to off-white crystalline powder

• Assay: ≥98.0%

• Melting Point: 116–122°C

• Density: ~1.39 g/cm³

• Solubility: Soluble in THF, DCM, DMF, Acetonitrile; reacts with water

• Moisture Sensitive

• Storage: Store under inert atmosphere in a cool, dry place (0–10°C recommended) 

Description

1,1'-Carbonyldiimidazole (CDI) is a highly efficient carbonylating and coupling reagent widely used in pharmaceutical, peptide, and fine chemical synthesis. CDI activates carboxylic acids under mild conditions, facilitating the formation of amides, esters, carbamates, and ureas with high yields and minimal by-products. Due to its ease of handling and clean reaction profile, CDI is a preferred reagent in API development and commercial manufacturing. 

Keywords

CDI, Carbonyldiimidazole, 1,1'-Carbonyldiimidazole, CAS 530-62-1, Peptide Coupling Reagent, Carbonylating Agent, Pharmaceutical Intermediate, API Intermediate, Amide Synthesis, Green Chemistry Reagent.