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Psoralen
Psoralen
Psoralen

Psoralen

Price USD2.00
Packge 1kg
  • Min. Order:1kg
  • Supply Ability:100kg
  • Time:2019-07-06

Product Details

  • Product NamePsoralen
  • CAS No.66-97-7
  • EINECS No.200-639-7
  • MFC11H6O3
  • MW186.16
  • InChIKeyZCCUUQDIBDJBTK-UHFFFAOYSA-N
  • AppearanceneatWhite to Off-White
  • storage temp. 2-8°C
  • Melting point 160-162 °C
  • Boiling point 280.64°C (rough estimate)
  • density 1.2477 (rough estimate)
  • Water Solubility 65.16mg/L(25 ºC)
Psoralen Basic information
Description References
Product Name: Psoralen
Synonyms: PSORALEN;7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE;7h-furo[3,2-g]benzopyran-7-one;FURO[3,2-G]BENZOPYRAN-7-ONE;FURO[3,2-G]COUMARIN;FICUSIN;2-Propenoic acid, 3-(6-hydroxy-5-benzofuranyl)-, delta-lactone;2-Propenoicacid,3-(6-hydroxy-5-benzofuranyl)-,δ-lactone
CAS: 66-97-7
MF: C11H6O3
MW: 186.16
EINECS: 200-639-7
Product Categories: Coumarins;Intermediates & Fine Chemicals;Pharmaceuticals;Heterocycles;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors
Mol File: 66-97-7.mol
Psoralen Structure
 
Psoralen Chemical Properties
Melting point  160-162 °C
Boiling point  280.64°C (rough estimate)
density  1.2477 (rough estimate)
refractive index  1.6310 (estimate)
storage temp.  2-8°C
λmax 328nm(EtOH)(lit.)
Merck  14,7928
InChIKey ZCCUUQDIBDJBTK-UHFFFAOYSA-N
CAS DataBase Reference 66-97-7(CAS DataBase Reference)
NIST Chemistry Reference 7H-furo[3,2-g][1]benzopyran-7-one(66-97-7)
 
Safety Information
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26
WGK Germany  3
RTECS  LV0944000
8-10
HS Code  29339900
Hazardous Substances Data 66-97-7(Hazardous Substances Data)
MSDS Information
Provider Language
SigmaAldrich English
 
Psoralen Usage And Synthesis
Description Psoralen is a kind of naturally occurring furocoumarin. It is naturally occurred in the seeds of Psoralea corylifolia as well as in the common fig, celery, parsley, West Indian Satinwood and all citrus fruits. It is capable of binding to DNA via single- and double-strand cross-linking upon photoactivation with UV radiation. It can intercalate with DNA, blocking its synthesis and cell division. For this reason, it is an important mutagen and can be used in related molecular biology studies. It also exhibits anti- proliferative, anti-allergenic and anti-histamine functions. It can also be used in PUVA treatment for skin diseases such as psoriasis, eczema and vitiligo. It is also effective tanning activator in sunscreens. Some of its derivatives, e.g. amino-psoralen, amotosalen HCl, can even inactivate pathogens in blood products.
References https://en.wikipedia.org/wiki/Psoralen
https://pubchem.ncbi.nlm.nih.gov/compound/Psoralen#section=Top
Chemical Properties Crystalline Solid
Uses Use as photochemical probe in biological systems
Uses Psoralens are phytoalexins; they are used by plants in a defensive response to attacks by fungi and insects. They have also shown photosensitizing and phototoxic effects in animals and humans and have been used in photochemotherapy for management of vitiligo, psoriasis, and mycosis fungoides. Used as photochemical probe in biological systems.
Definition ChEBI: The simplest member of the class of psoralens that is 7H-furo[3,2-g]chromene having a keto group at position 7. It has been found in plants like Psoralea corylifolia and Ficus salicifolia.
Uses As photochemical probe in biological systems: P.-S. Song, C.-N. Ou, Ann. N.Y. Acad. Sci. 346, 355 (1980).
 
Psoralen Preparation Products And Raw materials
 
Tag:Psoralen(66-97-7) Related Product Information2-Oxo-(2H)-furo(2,3-h)-1-benzopyran Psoralen-mop BAVACHIN benzopyran CoumarinPsoralen 7H-Furo3,2-g1benzopyran-7-one, 3-methoxy-2-(1-methylethyl)- BergamotineOXYPEUCEDANIN ISOPIMPINELLIN 3-(HYDROXYMETHYL)-2,5,9-TRIMETHYL-7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE ALLOISOIMPERATORIN XANTHOTOXOL TRIOXSALEN, 4'-AMINOMETHYL-, HYDROCHLORIDE Imperatorin TRIOXSALEN, 4'-HYDROXYMETHYL- AKOS 211-03 Bergapten
 
 

Company Profile Introduction

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate,  is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
 
Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
 
  • Since:2014-12-17
  • Address: No.967,15th Floor,Unit 7, Building 1, No.70 of DianChang Road, High-tech Development Zone, Zhengzho
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