(2-Bromoethyl)benzene

Melting point - 56 ° C  

The boiling point of 220-221 ° C (lit.)  

At 25 °C(lit.)  

Refractive index N20 /D 1.556(lit.)  

Flash point 193 ° F  

Storage conditions 2-8°C  

The solubility of 0.039 g/l  

Liquid form  

Color Clear colorless to pale yellow  

Water soluble  INSOLUBLE

β -bromophenyl ethane is an important intermediate in the synthesis of high efficiency bromo-based flame retardant polystyrene, and is also often used in the preparation of organic synthesis intermediates.  Such as β -bromobenzethane can be used to prepare the pulenstra intermediate 4-(4-phenylbutoxy) benzoic acid.  

Prelstra was first developed as an anti-asthma drug by The Japanese company Ono and was marketed in Japan in 1995. In 1999, prelstra was found to treat allergic rhinitis.  Pulenstra is a leukotriene C4/D4 receptor antagonistic antibody (lTRAs) with very low toxicity. It can selectively inhibit the activity of leukotriene multiple skin in airway smooth muscle, and has almost no effect on arachidonic acid metabolic enzymes, and has no antagonistic effect on acetylcholine and 5-hydroxytryptamine, and has significant inhibition on lTC4, lTD4 and lTE4.  

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