Product Details
- Product NameProchlorperazine
- CAS No.58-38-8
- EINECS No.200-379-4
- MFC20H24ClN3S
- MW373.94
- AppearanceSolidWhite to Yellow Oil to Waxy
- Melting point 228 °C
- density 1.1679 (rough estimate)
- Boiling point 260-275 °C(Press: 2 Torr)
- Water Solubility 14.96mg/L(24 ºC)
- storage temp. Refrigerator
Amy 376 Email: amy@coreychem.com
Career Henan Chemical Co
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| Prochlorperazine Basic information |
| Product Name: |
Prochlorperazine |
| Synonyms: |
10H-Phenothiazine, 2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-;2-Chloro-10-(3-(1-methyl-4-piperazinyl)-propyl)-phenothiazine;2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-10h-phenothiazin;2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-phenothiazin;2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine;2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine;3-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine;3-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine |
| CAS: |
58-38-8 |
| MF: |
C20H24ClN3S |
| MW: |
373.94 |
| EINECS: |
200-379-4 |
| Product Categories: |
COMPAZINE;Organics |
| Mol File: |
58-38-8.mol |
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| |
| Prochlorperazine Chemical Properties |
| Melting point |
228 °C |
| Boiling point |
260-275 °C(Press: 2 Torr) |
| density |
1.1679 (rough estimate) |
| refractive index |
1.6000 (estimate) |
| pka |
pKa 8.1(H2O,t =24±1,I undefined) (Uncertain) |
| Water Solubility |
14.96mg/L(24 ºC) |
| CAS DataBase Reference |
58-38-8(CAS DataBase Reference) |
| NIST Chemistry Reference |
Prochlorperazine(58-38-8) |
| |
| Prochlorperazine Usage And Synthesis |
| Uses |
antiemetic, antipsychotic, treatment of vertigo |
| Definition |
ChEBI: A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position. |
| Brand name |
Compazine (GlaxoSmithKline). |
| Safety Profile |
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Experimental teratogenic and reproductive effects. Human systemic effects by ingestion: headache, blood pressure elevation. Implicated in aplastic anemia. When heated to decomposition it emits very toxic fumes of SOx, NOx, and Cl-. |
| Veterinary Drugs and Treatments |
Prochlorperazine as a single agent is used in dogs and cats as an antiemetic. The only approved products for animals are combination products containing prochlorperazine, isopropamide, with or without neomycin (Darbazine?, Neo-Darbazine?—SKB Labs) which are no longer marketed in the USA. The approved indications for these products include: vomiting, non-specific gastroenteritis, drug induced diarrhea, infectious diarrhea, spastic colitis, and motion sickness in dogs and cats (injectable product only). |
Company Profile
Introduction
Technology research and transfer of pilot screening, pilot scale-up and mass production solutions , for pharmaceutical intermediates, biologicals and fine chemicals (Not including inflammable , explosive , hazardous goods ) ; Market : Nano material , metal catalyst , raw material of cosmetics , pharmaceutical intermediates , chemicals , photoelectric material , import and export of technology and goods (For projects subject to approval according to law, business activities can be carried out only after approval by relevant departments ).
