Cetilistat

Price	USD450.00
Packge	1KG

Min. Order:1g
Supply Ability:1000kg
Time:2021-12-23

Product Details

Product NameCetilistat
CAS No.282526-98-1
EINECS No.1532714-185-1
MFC25H39NO3
MW401.58
AppearanceSolidWhite to Off-White
density 1.02
Melting point 72.0 to 76.0 °C
Boiling point 509.7±43.0 °C(Predicted)
storage temp. 2-8°C

Product Name: Cetilistat

CAS: 282526-98-1

MF: C25H39NO3

MW: 401.58

Description cetilistat works via inhibition of pancreatic lipases in the gut to inhibit fat absorption and thereby reduce caloric uptake from diet. The medicinal chemistry program has not been described in the scientific literature, but the patent describing cetilistat also describes the synthesis of analogs with varied aryl substituents and lipophilic tails. The synthesis of cetilistat involves condensation of a hexadecylcarbonochloridate with 2-amino-5-methylbenzoic acid; other analogs were synthesized by varying the carbonochloridate and 2-aminobenzoic acid components. Cetilistat is a potent inhibitor of human and rat pancreatic lipase with IC50s of 15 and 136 nM, respectively, with little inhibition of trypsin or chymotrypsin.

Chemical Properties Off-white Cryst

Uses A novel pancreatic lipase inhibitor for the treatment of obesity in both diabetic and non-diabetic patients.

Company Profile Introduction

WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD is located in Jiangxia District, Wuhan City, Hubei Province. Main pharmaceutical intermediates, raw materials, food additives, antibiotics raw materials, etc. Wuhan dongkangyuan Technology Co., Ltd. is located in Wuhan, the thoroughfare of nine provinces. It is a high-tech industrial company specializing in the R & D and sales of chemical raw materials in Central China. The company has its own R & D base, equipped with advanced production equipment and high-efficiency precision testing instruments, with a complete, scientific and quality management system. And constantly committed to technological innovation, product innovation and management innovation, with high-tech and excellent innovation quality service has won the trust of University organs, scientific research institutions, pharmaceutical manufacturers, quality inspection departments, environmental protection enterprises, chemical production, agricultural production, food related industries and other industries. In order to ensure that our products in the same industry with super competitiveness. The company has independent import and export operation rights and excellent sales team.

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WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD

Hubei CHINA

Since:2013-04-05
Address: Yuanfen Road community, Wuchang District, Wuhan City

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