65-49-6
Product Name:
4-Aminosalicylic acid
Formula:
C7H7NO3
Synonyms:
4-Amino-2-hydroxybenzoic acid;4-Aminosalicylic acid;PAS
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | White or nearly white solid; Affected by light and air; [Hawley] Beige powder; [MSDSonline] |
|---|---|
| Color/Form | MINUTE CRYSTALS FROM ALC |
| Odor | ODORLESS, OR HAS SLIGHT ACETOUS ODOR |
| Melting Point | 150.5 dec °C |
| Solubility | >23 [ug/mL] (The mean of the results at pH 7.4) |
| Vapor Pressure | 0.000004 [mmHg] |
| LogP | 0.89 |
| Stability/Shelf Life | DARKENS ON EXPOSURE TO LIGHT & AIR |
| pH | PH (SATURATED AQ SOLN): BETWEEN 3 & 3.7 |
| Dissociation Constants | 3.625 |
| Other Experimental Properties | PH OF 0.1% AQ SOLN: 3.5 |
| Chemical Classes | Nitrogen Compounds -> Aminobenzoic Acids |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
COMPUTED DESCRIPTORS
| Molecular Weight | 153.14 g/mol |
|---|---|
| XLogP3 | 1.3 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 1 |
| Exact Mass | 153.042593085 g/mol |
| Monoisotopic Mass | 153.042593085 g/mol |
| Topological Polar Surface Area | 83.6 Ų |
| Heavy Atom Count | 11 |
| Formal Charge | 0 |
| Complexity | 160 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
4-aminosalicylic acid is an aminobenzoic acid that is salicylic acid substituted by an amino group at position 4. It has a role as an antitubercular agent. It is an aminobenzoic acid and a member of phenols. It is functionally related to a salicylic acid. It is a conjugate acid of a 4-aminosalicylate(1-).