CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Color/Form | Crystals |
| Solubility | In water, 140 mg/L at 25 °C |
| LogP | log Kow = 1.67 |
| Stability/Shelf Life | Fludrocortisone acetate tablets should be stored in well-closed containers at room temperature; excessive heat should be avoided. /Fludrocortisone acetate/ |
| Optical Rotation | Specific optical rotation: 139 deg at 23 °C/D (c= 0.55 in 95% ethanol) |
| Other Experimental Properties | DECOMPOSES @ 260-262 °C |
COMPUTED DESCRIPTORS
| Molecular Weight | 380.4 g/mol |
|---|---|
| XLogP3 | 1.7 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 2 |
| Exact Mass | 380.19990218 g/mol |
| Monoisotopic Mass | 380.19990218 g/mol |
| Topological Polar Surface Area | 94.8 Ų |
| Heavy Atom Count | 27 |
| Formal Charge | 0 |
| Complexity | 734 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 7 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Fludrocortisone is a C21-steroid, a 3-oxo-Delta(4) steroid, a 20-oxo steroid, a 21-hydroxy steroid, a fluorinated steroid, a mineralocorticoid, a 17alpha-hydroxy steroid and an 11beta-hydroxy steroid. It has a role as an adrenergic agent and an anti-inflammatory drug. It derives from a hydride of a pregnane.