127-07-1
Product Name:
Hydroxyurea
Formula:
CH4N2O2
Synonyms:
Hydroxycarbamide;Hydroxyurea;Hydroxyurea - CAS 127-07-1 - Calbiochem;Ribonucleotide Reductase Inhibitor I, RNR Inhibitor I
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Hydroxyurea appears as odorless or almost odorless white to off-white crystalline solid. Tasteless. (NTP, 1992) |
|---|---|
| Color/Form | Needles from alcohol |
| Boiling Point | Decomposes (NTP, 1992) |
| Melting Point | 291 to 295 °F (decomposes) (NTP, 1992) |
| Solubility | greater than or equal to 100 mg/mL at 70 °F (NTP, 1992) |
| LogP | -1.8 |
| LogS | 1.12 |
| Stability/Shelf Life | Stable under recommended storage conditions. |
| Other Experimental Properties | Crystals in 2 forms. MP form 1: 70-72 °C (decomposes); MP form 2: 141 °C |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H340:Germ cell mutagenicity H361:Reproductive toxicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P308+P313:IF exposed or concerned: Get medical advice/attention. |
COMPUTED DESCRIPTORS
| Molecular Weight | 76.055 g/mol |
|---|---|
| XLogP3 | -1.8 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 0 |
| Exact Mass | 76.027277375 g/mol |
| Monoisotopic Mass | 76.027277375 g/mol |
| Topological Polar Surface Area | 75.4 Ų |
| Heavy Atom Count | 5 |
| Formal Charge | 0 |
| Complexity | 42.9 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Hydroxyurea appears as odorless or almost odorless white to off-white crystalline solid. Tasteless. (NTP, 1992)