112529-15-4
Product Name:
Pioglitazone hydrochloride
Formula:
C19H21ClN2O3S
Synonyms:
5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione monohydrochloride;5-[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyl]thiazolidine-2,4-dione hydrochloride;Pioglitazone hydrochloride
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Solubility | 1.8 [ug/mL] (The mean of the results at pH 7.4) |
|---|---|
| Collision Cross Section | 178 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P337+P313:IF eye irritation persists: Get medical advice/attention. |
COMPUTED DESCRIPTORS
| Molecular Weight | 392.9 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 7 |
| Exact Mass | 392.0961414 g/mol |
| Monoisotopic Mass | 392.0961414 g/mol |
| Topological Polar Surface Area | 93.6 Ų |
| Heavy Atom Count | 26 |
| Formal Charge | 0 |
| Complexity | 466 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Pioglitazone hydrochloride is a thiazolidinedione, it can increases the body's sensitivity to insulin. It is used for type 2 diabetes, not type 1 diabetes or diabetic ketoacidosis.