Venlafaxine hydrochloride
Synonym(s):(+/-)-1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride;Effexor;Venlafaxine hydrochloride
- CAS NO.:99300-78-4
- Empirical Formula: C17H28ClNO2
- Molecular Weight: 313.86
- MDL number: MFCD03658865
- EINECS: 619-421-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-23 16:18:34
What is Venlafaxine hydrochloride ?
Description
Venlafaxine hydrochloride, a novel phenethylamine derivative, was introduced in the U.S.A. as an antidepressant. Venlafaxine is reported to be the first in the class of the second-generation of antidepressants with dual serotonidnorepinephrine reuptake inhibitory activity. Venlafaxine lacks any affinity for muscarinic, cholinergic, histaminergic and noradrenergic receptors and therefore, has an unusually favorable side effect profile compared with classical tricyclic antidepressants and shows less cardiotoxicity. In addition, venlafaxine has a rapid onset of action that makes it unique among the antidepressant agents. Other indications for venlafaxine include the treatment of obsessive and panic disorders, and obesity. Both enantiomers of venlafaxine were reported to have similar biological activity.
The Uses of Venlafaxine hydrochloride
Venlafaxine hydrochloride is an inhibitor of reuptake of both serotonin (IC50 = 0.21 μM) and norepinephrine (IC50 = 0.64 μM). It is effective in vitro and in vivo and against human as well as rat receptors. As an antidepressant, it is properly placed in the serotonin-norepinephrine reuptake inhibitor class.[Cayman Chemical]
What are the applications of Application
Venlafaxine Hydrochloride is an inhibitor of ST and SLC6A2
Properties of Venlafaxine hydrochloride
Melting point: | 207-209°C |
Flash point: | 9℃ |
storage temp. | 2-8°C |
solubility | H2O: >10mg/mL |
form | powder |
color | white |
Safety information for Venlafaxine hydrochloride
Signal word | Danger |
Pictogram(s) |
Environment GHS09 |
GHS Hazard Statements |
H411:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P273:Avoid release to the environment. P391:Collect spillage. Hazardous to the aquatic environment P501:Dispose of contents/container to..… |
Computed Descriptors for Venlafaxine hydrochloride
InChIKey | QYRYFNHXARDNFZ-UHFFFAOYSA-N |
Abamectin manufacturer
GLP Pharma Standards
ASCENT FINE CHEM
SYNTHINK RESEARCH CHEMICALS
KARPSCHEM LABORATORIES PVT. LTD.
Alembic Pharmaceuticals Limited
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