Moxifloxacin hydrochloride
Synonym(s):12-8039;1-Cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydropyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride;Avalox;BAY12-8039;Moxifloxacin hydrochloride
- CAS NO.:186826-86-8
- Empirical Formula: C21H25ClFN3O4
- Molecular Weight: 437.8923032
- MDL number: MFCD00949117
- EINECS: 641-756-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-18 08:51:57
What is Moxifloxacin hydrochloride?
Description
Moxifioxacin hydrochlodde is one of the two new fluoroquinolonecarboxylic acid antibiotics introduced in 1999 for the treatment of respiratory tract infections such as community-acquired pneumonia, acute exacerbations of bronchitis or acute sinusitis. Moxifloxacin can be synthesized through a 12 step sequence from the classical 4-quinolone-3-carboxylic acid template. Some advantages of Moxifloxacin over Ciprofloxacin, another of Bayer's launched quinolones, have been shown, i.e. an enhanced activity against Gram-positive bacteria (Streptococcus pneumoniae, Clostndium pneumoniae), a favorable pharmacokinetic profile (good tissue penetration and plasma concentrations above MICs) and a lack of phototoxicity (UVA irradiation).
The Uses of Moxifloxacin hydrochloride
Moxifloxacin Hydrochloride is an antibacterial agent that inhibits the activities of Topo II (DNA gyrase) and topoisomerase IV.
Side Effects
The possible serious side effects of moxifloxacin hydrochloride including: unusual bruising/bleeding, signs of a new infection (such as sore throat that doesn't go away, fever), signs of kidney problems (such as change in the amount of urine), signs of liver problems (such as nausea/vomiting that doesn't stop, unusual tiredness, stomach/abdominal pain, yellowing eyes/skin, dark urine).
Precautions
Before taking moxifloxacin hydrochloride, tell your doctor or pharmacist if you are allergic to it; or to other quinolone antibiotics (such as ciprofloxacin, levofloxacin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Properties of Moxifloxacin hydrochloride
Melting point: | Slightly yellow to yellow crystalline powder, mp 324-325° |
Boiling point: | 636℃ |
Flash point: | >110°(230°F) |
storage temp. | 2-8°C |
solubility | H2O: soluble5mg/mL, clear (warmed) |
form | powder |
color | white to beige |
Water Solubility | Sparingly soluble in water. Soluble in DMSO |
Safety information for Moxifloxacin hydrochloride
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H319:Serious eye damage/eye irritation H412:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Moxifloxacin hydrochloride
InChIKey | IDIIJJHBXUESQI-DFIJPDEKSA-N |
Abamectin manufacturer
BIOCHEMICAL & SYNTHETIC PRODUCTS PVT. LT.,
KARPSCHEM LABORATORIES PVT. LTD.
Nivika Chemo Pharma Pvt Ltd
SVK Laboratories Pvt Ltd
CNS CHEMICALS
Chemeca Drugs Private Limited (Vegesna Laboratories Pvt Ltd)
Anuh Pharma Ltd (SK GROUP)
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