5-(4-Bromophenyl)-4,6-dichloropyrimidine
- CAS NO.：146533-41-7
- Empirical Formula: C10H5BrCl2N2
- Molecular Weight: 303.97
- MDL number: MFCD13151897
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-04-24 17:21:40
What is 5-(4-Bromophenyl)-4,6-dichloropyrimidine?
Description
5 - (4-Bromophenyl)-4, 6- dichloropyrimidine is a key intermediate and has a wide range of applications in the pharmaceutical and chemical fields.
The Uses of 5-(4-Bromophenyl)-4,6-dichloropyrimidine
5-(4-Bromophenyl)-4,6-dichloropyrimidine is a reactant used in the synthesis of Macitentan, an orally active dual endothelin receptor antagonist.
Properties of 5-(4-Bromophenyl)-4,6-dichloropyrimidine
| Melting point: | 98.0 to 102.0 °C |
| Boiling point: | 368.7±42.0 °C(Predicted) |
| Density | 1.677±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly) |
| form | Solid |
| color | Off-White |
Safety information for 5-(4-Bromophenyl)-4,6-dichloropyrimidine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 5-(4-Bromophenyl)-4,6-dichloropyrimidine
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